A population of mice has black or brown hair. The gene for black hair color (B) is dominant over brown (b). If 16% of the mice are homozygous black and 24% are heterozygous black, what would be the frequency of each allele?. (p + q = 1, p2 + 2pq + q2 = 1). . is it (A. p=0.65, q=0.35 (B. p=0.25, q=0.75 (C. p=0.4, q=0.6
Given:
p + q = 1 ; p² + 2pq + q² = 1
let B substitute p ; let b substitute q.
B + b = 1 ; B² + 2Bb + b² = 1
B² = 16% or 0.16
B = √0.16 = 0.40
B + b = 1
0.40 + b = 1
b = 1 - 0.40
b = 0.60
answer is:
C) p = 0.4 ; q = 0.6
Answer:
Frequency of black allele is \(0.4\\\)
Frequency of brown allele is \(0.6\\\)
Explanation:
As per Hardy-Weinberg equation,
Frequency of the homozygous genotype is represented by AA and aa
Frequency of the heterozygous genotype is represented by Aa
In the Hardy-Weinberg mathematical equation
Frequency of AA is represented by \(q^2\\\)
Frequency of AA is represented by \(p^2\\\)
Frequency of AA is represented by \(pq\\\)
And the mathematical equation is as follows -
\(p^ 2 + q^ 2 + 2pq = 1\\\)
Substituting the given values in above equation we get
\(0.16 + q^2 + 2 (0.24) = 1\\q^2 = 1 - 0.16 - 2 (0.24)\\q = \sqrt{0.36} \\q = 0.6\\\)
Also, sum of the allele frequencies for all the alleles at the locus is equal to 1 which means
\(p + q = 1\\p + 0.6 = 1\\p = 0.4\\\)
Frequency of black allele is \(0.4\\\)
Frequency of brown allele is \(0.6\\\)