Why is the manner of Macduff's birth important?

AHe was born during the witching hour, and it was prophesied from his birth that he would defeat a great king.

BHe was trained as a soldier from birth and has seen many great battles, making him a more experienced fighter than Macbeth.

CHe was born by cesarean section and fulfills the witches' prophecy that only a man not born of a woman could kill Macbeth.

DHe was orphaned at a young age because Macbeth was responsible for his parents' deaths, and he has come to exact his revenge.