First, go ahead and set it up:
\(4x-9-(10x+5)\)
Now since you're subtracting that whole term, you must change the signs:
\(4x-9-10x-5\)
And now you simplify:
\(-14-6x\)
Then you can take out a -2 if you want:
\(-2(7+3x)\)
And that's your final answer!