Both make nucleotide sequences in the 5' to 3' direction is common to both DNA replication and transcription.
DNA replication is the process by which a DNA molecule generates two identical to itself.
- DNA polymerases can only synthesize DNA in the 5'-3 'direction, that is, they are only capable of adding nucleotides to the 3' OH end of another nucleotide triphosphate.
- DNA polymerases require a 3 'OH end to which to add nucleotide triphosphate to begin DNA synthesis.
DNA transcription is the synthesis of mRNA (messenger RNA) from DNA that will later be translated to form proteins.
- Specific regulatory sequences indicate the beginning and end of the DNA segments to be transcribed, as well as which of the two DNA strands to use as a template.
- The chain that serves as a template for the RNA is the 3′-5 ′ and is called sense, the other is the antisense whose sequence coincides with that of the transcribed mRNA.
Therefore, we can conclude that both make nucleotide sequences in the 5' to 3' direction is common to both DNA replication and transcription.
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