PKU and albinism are two autosomal recessive disorders,unlinked in human beings. if couple each of them heterozygous for both traits, produce a child, what is the chance of their having a child with (a)PKU (b)albinism (c)both traits?
Answer:
a) 3/16; b) 3/16; c) 1/16
Explanation:
PKU and albinism are two autosomal recessive disorders. The possible genotypes and phenotypes for each disease are:
PKU
Albinism
If a couple of individuals heterozygous for both genes (PpAa) has offspring, from the Punnett Square we get the chances of them having:
ppA_: 3/16
P_aa: 3/16
ppaa: 1/16