The DNA sequence TTG is changed to TCG and produces a new protein. Which type of mutation is this?

Amissense
Bnonsense
Csilent
Dframeshift

Verified Answer :

The answer isĀ A) Missense. The amino acid is being replaced by another amino acid in the DNA sequence TTG changing to TCG and producing a new protein.

The right answer is a) missense.


A missense mutation is a point mutation in which a nucleotide of a codon is changed, inducing the change of the associated amino acid. This can render the translated protein non-functional.


These mutations are responsible for diseases such as epidermolysis bullosa and sickle cell disease (which produces a new hemoglobin called Hemoglobin S).