Which of the following mechanism best describe the manner in which lysozyme lowers the energy required for its substrate to reach its transition state conformation? Explain your choice.

Aby binding two molecules and orienting them in a way that favors a reaction between them.

Bby altering the shape of the substrate to mimic the conformation of the transition state.

Cby speeding up the rate at which water molecules collide with the substrate.

Dby binding irreversibly to the substrate so that it cannot dissociate.