Glucose and amino acids need facilitated diffusion to move across the plasma membrane.
Facilitated diffusion is the movement of selective molecules across the cell or plasma membrane through the protein channels. The ions or molecules that move across the biological membrane by the help of specific integral trans-membrane proteins.
Glucose being a six carbon large molecule cannot be transported by the passive diffusion so it moves down the concentration gradient by facilitated diffusion. At the membrane, the carrier protein binds to glucose and alters its shape and then transports it from one side of the membrane to other.
The amino acids are also large molecules also get transported by the carrier trans-membrane proteins like permeases by altering their shape or conformation.
