Test your understanding of the term denaturation by deciding which of the following statements are true. 1- Protein denaturation involves cleavage of its peptide bonds. 2- Denaturation of an enzyme will cause a loss of its catalytic activity. 3- Denaturation and digestion refer to the same process. 4- A denatured protein has a different primary structure than its native state. 5- A denatured protein has a different tertiary structure than its native state.