Histamine is a chemical substance released in inflammatory and allergic responses. The histamine H1 receptor o? Histamine is a chemical substance released in inflammatory and allergic responses. The histamine H1 receptor on target cells is a G protein-coupled receptor that activates phospholipase C in response to the binding of histamine. Which statement about the binding of histamine to the histamine H1 receptor is false?
AHistamine binds extracellularly to the H1 receptor.
BWhen histamine binds to the H1 receptor, the receptor undergoes a conformation change and binds the inactive G protein.
CHistamine binds intracellularly to the inactive G protein, activating the G protein.
DOnce the G protein is active, it binds to the enzyme phospholipase C, activating it. e. Histamine is likely hydrophilic.
AHistamine binds extracellularly to the H1 receptor.
BWhen histamine binds to the H1 receptor, the receptor undergoes a conformation change and binds the inactive G protein.
CHistamine binds intracellularly to the inactive G protein, activating the G protein.
DOnce the G protein is active, it binds to the enzyme phospholipase C, activating it. e. Histamine is likely hydrophilic.