Verified Answer :

It would probably be the death of the main character or
characters due to some event that casts a dark shadow on them.  It may be due to rejection or revenge because
a deed the character committed.  It can
also be something that they failed to do that would have averted such an
unfortunate outcome.  One is for sure and
that is someone will die here.

For Apex the answer is "Characters suffer due to personal flaws."