Answer:
The most appropriate answer would be mutations.
Mutation refers to random and permanent change or alterations occur in the nucleotide sequence of the genome of an organism.
Few mutations also take place during the DNA replication process.
However, DNA polymerase also has proofreading property by which it checks for the mismatch or mis-paired bases and corrects it.
Thus, DNA polymerase helps in reducing mutations by its proofreading property.
